Date of Graduation

Spring 5-25-2015

Document Type


Degree Name

Master of Science in Chemistry



First Advisor

Lawrence D. Margerum


In an effort to synthesize a novel silica nanoparticle platform for the fluorescent sensing of metal ions and future use in QDA, we synthesized from the bottom up a novel 2, 2’: 2’, 6- terpyridine functionalized fluorescein doped silica nanoparticle system capable of the sensitive detection of Cu2+ and Co2+. To further probe the properties of our nanoparticle system, we substitute the fluorescein dye of rhodamine and have observed differences in the selectivity and sensitivity of the system indicative of the potential customizability of the system. Initial QDA results on the fluorescein system suggest that while the signal is returned upon the introduction of EDTA, L-histidine, and epinephrine, the fluorescein dye in our system may interact with many of the anions tested.