Date of Graduation

Spring 5-22-2015

Document Access

Project/Capstone - Global access

Degree Name

Master of Science in Nursing (MSN)


School of Nursing and Health Professions

First Advisor

Lynn Obrien, NP

Second Advisor

Dr. Melissa Vandeveer, PNP, CNL, PhD


In 2012, the US Food and Drug Administration approved the pill Truvada for use as pre-exposure prophylaxis or PrEP. Its purpose is to help prevent HIV infection by taking one pill every day. This project aims to improve PrEP patient education provided by the multi-disciplinary team and to decrease new HIV infection and sexually transmitted infections (STIs) to zero. The focus of the study is patients on PrEP at the Infectious Disease and HIV Clinic in San Francisco Veterans Administration Medical Center. The Clinical Nurse Leader, in collaboration with the multidisciplinary team, incorporated Pender’s Health Promotion Model Theory in developing the teaching strategies. Strategies include revision of the current PrEP standard operating procedure, development of checklist for providers, two-session risk reduction class, improvement of the tracking system of patients’ adherence to scheduled follow-up appointments, and development of a clinic specific educational material. Review of the electronic medical record revealed 100% patient-education by the providers and zero new HIV infections and STIs. Literature review asserts that the use of multi-modal intervention to support PrEP adherence is an effective intervention. Recommendations include review and revision of the SOP and educational material every 6 months based on new evidence-based practices.