Date of Graduation

Fall 12-16-2022

Document Access

Project/Capstone - Global access

Degree Name

Master of Science in Nursing (MSN)


School of Nursing and Health Professions


MSN project

First Advisor

Mallory Manuel


This quality improvement project implements educational materials informed by organization-dependent nursing informatics and SEP-1 campaign metrics to improve early sepsis management compliance in the emergency department setting. The microsystem scored below a 90% compliance target in first vital to lactic acid result within one hour, lactic acid result to antibiotic administration within one hour, and antibiotic order to administration within thirty-five minutes before implementation. Factors identified as contributing to low compliance include rates of timely and accurate sepsis screening, use of a standardized sepsis order set, and intervention documentation. An educational inservice covering correct sepsis workflow in the electronic health record was implemented and addressed a computer-assisted sepsis triage and screening algorithm, correct use of a nurse-driven order set, and documentation of interventions as part of the SEP-1 Bundle. After implementation, all three compliance outcome measures saw improvement. SEP-1 compliant care increased through this change process.