Date of Submission

Summer 8-13-2024

Document Type

Manuscript

Degree Name

Doctor of Nursing Practice (DNP)

Department

Nursing

First Advisor

Alicia Kletter

Second Advisor

Mary Lou De Natale

Third Advisor

Trinette Radasa

Abstract

Schizophrenia cases and their associated healthcare costs have drastically increased over time in the U.S. Antipsychotic non-adherence is a primary contributor to the high rates of relapse and rehospitalization among the schizophrenic adult population. The development of long-acting injectable antipsychotics (LAIs) has positively impacted medication adherence, however, this treatment modality is still underemployed in practice due to barriers, such as physician and patient negative attitudes toward LAIs and lack of education. Nurses are in a great position to address these barriers as they serve as mediators between providers and patients. This literature review aims to discover evidence that LAI education for registered nurses improves overall knowledge, confidence, and attitudes on LAI treatment and its impact on medication adherence and rehospitalization. Despite the limited data on LAI education for nurses, results show that nursing education has a positive impact on nursing knowledge, attitudes, and confidence, as well as patient outcomes. Through LAI nursing education, nurses will become well-versed and confident in sharing their knowledge and advocating for the best course of treatment during shared decision-making moments with patients and providers, potentially opening the door for increasing LAI use in practice.

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